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Emitelsa.com has a Worldwide ranking of n/a Down n/a and ranking n/a in n/a. Using IP address 206.188.192.55 in and found 15 Other Websites on this Server

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Domain Age: 8 years, 280 days (Creation Date: 2010-07-17)

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  • Domain: Emitelsa.com
  • Hostname: Vux.netsolhost.com
  • Name Servers:

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  • Continent Code: NA
  • Country Code: US
  • Country Code3: USA
  • Country Name: United States
  • Region: FL
  • City: Jacksonville
  • Postal Code: 32258
  • Latitude: 30.143800735474
  • Longitude: -81.540100097656
  • Dma Code: 561
  • Area Code: 904

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Websites Same Server on IP 206.188.192.55

We Found 15 domains on IP 206.188.192.55 listing below the same server this website

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Imetelstat | Myelofibrosis | Myelodysplastic Syndromes | Geron

Imetelstat binds with high affinity to the template region of the RNA component of telomerase, resulting in direct, competitive inhibition of telomerase enzymatic activity, rather than elicit its effect through an antisense inhibition of protein translation. Imetelstat is administered by intravenous infusion.

Link: https://www.geron.com/r-d/imetelstat/ (Actived: Saturday Apr 20, 2019)

imetelstat.info

Imetelstat inhibits the activity of telomerase, which is an enzyme present in most types of cancer that enables tumor cells to replicate indefinitely. The purpose of imetelstat.info is to provide easy access to existing information about imetelstat, its basic workings, clinical potential and results from preclinical and clinical studies.

Link: https://imetelstat.eu/ (Actived: Friday Apr 19, 2019)

emitelsa.com - CanalSat Haïti

CANALSAT HAITI +509 2947-4141 | +509 2946-4141 | +509 2816-4242 | +509 2816-4343 Angle Rues Faustin 1er & Cheriez (Canape-Vert), HT 6110 Port-au-Prince, Haiti

Link: http://www.emitelsa.com/ (Actived: Saturday Apr 20, 2019)

IMETELSTAT « New Drug Approvals

Imetelstat sodium is a novel, first-in-class telomerase inhibitor that is a covalently-lipidated 13-mer oligonucleotide (shown below) complimentary to the human telomerase RNA (hTR) template region. Imetelstat sodium does not function through an anti-sense mechanism and therefore lacks the side effects commonly observed with such therapies.

Link: https://newdrugapprovals.org/2019/01/28/imetelstat/ (Actived: Tuesday Apr 9, 2019)

Clinical Trials for Imetelstat | Geron

Imetelstat, a first-in-class telomerase inhibitor and our sole product candidate, is being developed for the potential treatment of hematologic myeloid malignancies. Imetelstat is currently in two clinical trials which were originally conducted by Janssen Research and Development (Janssen) under a collaboration agreement (see Partners). Geron

Link: https://www.geron.com/patients/clinical-trials/ (Actived: Friday Apr 19, 2019)

Imetelstat | C148H211N68O53P13S13 - PubChem

Imetelstat | C148H211N68O53P13S13 | CID 91869396 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological

Link: https://pubchem.ncbi.nlm.nih.gov/compound/91869396 (Actived: Tuesday Apr 16, 2019)

IMETELSTAT – Drug Approvals International

Imetelstat sodium is a novel, first-in-class telomerase inhibitor that is a covalently-lipidated 13-mer oligonucleotide (shown below) complimentary to the human telomerase RNA (hTR) template region. Imetelstat sodium does not function through an anti-sense mechanism and therefore lacks the side effects commonly observed with such therapies.

Link: http://drugapprovalsint.com/imetelstat/ (Actived: Saturday Apr 20, 2019)

A Pilot Study of the Telomerase Inhibitor Imetelstat for ...

Imetelstat was administered as a 2-hour intravenous infusion (starting dose, 9.4 mg per kilogram of body weight) every 1 to 3 weeks. The primary end point was the overall response rate, and the

Link: https://www.nejm.org/doi/full/10.1056/NEJMoa1310523 (Actived: Thursday Dec 4, 2014)

Geron's Imetelstat: Obstacles To Success - Geron ...

Imetelstat is very promising, but telomerase inhibition is highly complex. Geron, if successful, could be an investment that changes your financial life. However, I highly doubt this is an

Link: https://seekingalpha.com/article/4097709-gerons-imetelstat-obstacles-success (Actived: Thursday Aug 10, 2017)

Definition of imetelstat sodium - NCI Drug Dictionary ...

The sodium salt of imetelstat, a synthetic lipid-conjugated, 13-mer oligonucleotide N3' P5'-thio-phosphoramidate with potential antineoplastic activity. Complementary to the template region of telomerase RNA (hTR), imetelstat acts as a competitive enzyme inhibitor that binds and blocks the active site of the enzyme (a "telomerase template antagonist"), a mechanism of action which differs from

Link: https://www.cancer.gov/publications/dictionaries/cancer-drug/def/imetelstat-sodium (Actived: Sunday Apr 14, 2019)

Commercial - imetelstat

2018 (08-02-2018) - Janssen BioTech applies for global patent for COMBINATION TREATMENT FOR HEMATOLOGICAL CANCERS, including Imetelstat. The present invention relates to a combination treatment for hematological cancers. More specifically; a combination of a telomerase inhibitor and a Bcl-2 inhibitor are useful in treating hematological cancers, including AML.

Link: https://imetelstat.eu/commercial (Actived: Thursday Apr 18, 2019)

Geron Corporation - Wikipedia

Geron Corporation has sponsored human clinical trials of several anti-cancer products. GRN163L (Imetelstat), is a drug that targets telomerase. In studies conducted at Johns Hopkins University, GRN163L was active against both CD138+ and CD138neg cancer stem cells and eliminated the colony forming potential of both by five weeks.

Link: https://en.m.wikipedia.org/wiki/Imetelstat (Actived: Saturday Apr 13, 2019)

The Toxicity Of Geron's Imetelstat May Lead To Accelerated ...

Imetelstat is currently being investigated in two late Phase II trials, IMerge and IMbark. The IMbark trial is a Phase 2 clinical trial evaluating Imetelstat in patients with intermediate-2 or

Link: https://seekingalpha.com/article/4137225-toxicity-gerons-imetelstat-may-lead-accelerated-fda-approval (Actived: Friday Jan 12, 2018)

Imetelstat - Geron Corporation - AdisInsight

Imetelstat, a first-in-class telomerase inhibitor, is being developed by Geron Corporation as an intravenous treatment for haematological myeloid malignancies.

Link: http://adisinsight.springer.com/drugs/800011270 (Actived: Tuesday Apr 9, 2019)

A Close Look at Geron’s Imetelstat - marketrealist.com

Geron contributes 50% of the development costs for the imetelstat trials. Imetelstat was granted fast track designation by the FDA in October 2017.

Link: https://marketrealist.com/2018/03/a-close-look-at-gerons-imetelstat (Actived: Tuesday Mar 20, 2018)

CanalSat Haïti

CANALSAT HAITI +509 2947-4141 | +509 2946-4141 | +509 2816-4242 | +509 2816-4343 Angle Rues Faustin 1er & Cheriez (Canape-Vert), HT 6110 Port-au-Prince, Haiti

Link: http://emitelsa.com/welcome/abonnement (Actived: Monday Apr 8, 2019)

Geron Announces Expansion of Leadership Team with ...

Imetelstat is a novel, first-in-class telomerase inhibitor exclusively owned by Geron and being developed in hematologic myeloid malignancies. Early clinical data suggest imetelstat may have

Link: https://www.globenewswire.com/news-release/2019/01/31/1708811/0/en/Geron-Announces-Expansion-of-Leadership-Team-with-Appointment-of-Chief-Medical-Officer.html (Actived: Thursday Jan 31, 2019)

Imetelstat Sodium in Treating Patients With Primary or ...

Imetelstat Sodium in Treating Patients With Primary or Secondary Myelofibrosis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.

Link: https://clinicaltrials.gov/ct2/show/NCT01731951 (Actived: Thursday Jul 19, 2018)