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Organoid - Wikipedia

An organoid is a miniaturized and simplified version of an organ produced in vitro in three dimensions that shows realistic micro-anatomy. They are derived from one or a few cells from a tissue, embryonic stem cells or induced pluripotent stem cells, which can self-organize in three-dimensional culture owing to their self-renewal and differentiation capacities.

Link: https://en.wikipedia.org/wiki/Organoid (Actived: Thursday Jun 13, 2019)

Organoids: A new window into disease, development and ...

Organoids can range in size from less than the width of a hair to five millimeters. There are potentially as many types of organoids as there are different tissues and organs in the body. To date, researchers have been able to produce organoids that resemble the brain, kidney, lung, intestine, stomach, and liver, and many more are on the way.

Link: https://hsci.harvard.edu/organoids (Actived: Saturday Jun 15, 2019)

Method of the Year 2017: Organoids | Nature Methods

Organoids can contain an impressive range of cell types—kidney organoids, for example, have been reported to have at least ten, with genuinely complex structure.

Link: https://www.nature.com/articles/nmeth.4575 (Actived: Tuesday Jan 2, 2018)

Organoid Research - STEMCELL Technologies

Culturing Organoids To date, organoid culture systems have been developed to model tissue structures from all three primary cell lineages. 3,4,6 Although different tissues require their own specific culture methods, in general, appropriate pluripotent stem cells or tissue-specific progenitor cells are embedded in Matrigel®, or another appropriate extracellular matrix.

Link: https://www.stemcell.com/technical-resources/area-of-interest/organoid-research.html (Actived: Thursday Jun 13, 2019)

ORGANOID TECHNOLOGIES. See. Feel. Smell. Experience.

"The increasing urbanization and uprooting of human beings calls for a timely response with new, natural interior design concepts: Organoid natural surfaces." Mag. Christoph Egger,

Link: https://www.organoids.com/en/ (Actived: Saturday Jun 15, 2019)

Individual brain organoids reproducibly form cell ...

Single-cell RNA-sequencing analysis demonstrates that individual human brain organoids generate the cellular diversity of the cerebral cortex with organoid-to-organoid variability that is

Link: https://www.nature.com/articles/s41586-019-1289-x (Actived: Thursday Jun 13, 2019)

3D Organoid Culture: New In Vitro Models of Development ...

Figure 1. Mouse Intestinal Epithelial Organoids. 3D Organoids were generated from adult mouse intestinal tissue following the protocol outlined by Clevers et al. Science. 2013. Organoid cells begin to form lumens and bud structures at around day 3-5 in culture and form complex crypt-like structures around day 7-10.

Link: https://www.sigmaaldrich.com/technical-documents/articles/biology/cell-culture/3d-organoid-culture.html (Actived: Friday Jun 14, 2019)

Organoids | European Organoids Symposium 2019 | Lombardia

The European Organoids Symposium 2019 is an LSFM4LIFE (www.lsfm4life.eu)-powered conference on the present and future of human stem cell organoids in basic research and cell therapy

Link: https://www.eos2019.eu/ (Actived: Friday Jun 14, 2019)

Picture Show: Organoids: Cell Press

Organoids. In the 30 years since the advent of 3D culturing, organoid research has exploded. The incredible range of tissue models and techniques have also given way to some of the most captivating images being created in biology. In this edition of the Cell Picture Show, we showcase the beauty of 3D cultured organoids.

Link: https://www.cell.com/pictureshow/organoids (Actived: Friday Jun 14, 2019)

Organoids — Preclinical Models of Human Disease | NEJM

An organoid is a three-dimensional construct composed of multiple cell types that originates from stem cells through self-organization and can simulate the architecture and functionality of native

Link: https://www.nejm.org/doi/full/10.1056/NEJMra1806175 (Actived: Thursday Feb 7, 2019)

Overview - Intestinal Organoids - Organoids - Areas of ...

Intestinal organoids have been cultured with immune cells 10,11,33 by introduction of the non-epithelial cells in the extracellular matrix supporting the organoid culture, thus recapitulating the interactions expected to take place at the basolateral side of the epithelium.

Link: https://www.stemcell.com/technical-resources/area-of-interest/organoid-research/intestinal-research/overview.html (Actived: Saturday Jun 15, 2019)

What you need to know about organoids: An explainer for ...

Organoids have therapeutic potential, allowing researchers the possibility to test cancer treatments, for example, on a lab-grown sample of a patient’s tumor, or cystic fibrosis treatments on a patient’s gut organoid. But on a more basic level, organoids offer a new window into human development.

Link: https://journalistsresource.org/tip-sheets/research/organoid-brain-research-explainer/ (Actived: Wednesday Jun 12, 2019)

Modeling mouse and human development using organoid ...

In vitro three-dimensional (3D) cultures are emerging as novel systems with which to study tissue development, organogenesis and stem cell behavior ex vivo . When grown in a 3D environment, embryonic stem cells (ESCs) self-organize into organoids and acquire the right tissue patterning to develop into several endoderm- and ectoderm-derived tissues, mimicking their in vivo counterparts.

Link: http://dev.biologists.org/content/142/18/3113 (Actived: Saturday Jun 15, 2019)

Organoids for Virus Research ETN project | Organovir

Within organovir the research programme is a full package ITN programme which enables 15 ESRs to familiarize themselves not only with the scientific and technical aspects of innovative 3D culture systems for virus research, but also with the financial, commercial, ethical, communicative, policy and dissemination aspects enabling optimal valorisation of organoids.

Link: https://organovir.com/ (Actived: Thursday Jun 13, 2019)

Home - Cell Symposia: Engineering Organoids and Organs

The goal of this Cell Symposium is to bring scientists studying organoids and organ engineering together with bioengineers to discuss the exciting opportunities and challenges for engineering complexity in higher-order organ-like systems and to foster collaborations and synergize efforts toward generating cellular platforms that can address a

Link: http://www.cell-symposia.com/organoids-2019/ (Actived: Friday Jun 14, 2019)